Methylated DNA in Pancreatic Juice Distinguishes Patients With Pancreatic Cancer From Controls

BACKGROUND & AIMS: Precursors of pancreatic cancer arise in the ductal epithelium; markers exfoliated into pancreatic juice might be used to detect high-grade dysplasia (HGD) and cancer. Specific methylated DNA sequences in pancreatic tissue have been associated with adenocarcinoma. We analyzed...

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Published in:Clin Gastroenterol Hepatol
Main Authors: Majumder, Shounak, Raimondo, Massimo, Taylor, William R., Yab, Tracy C., Berger, Calise K., Dukek, Brian A., Cao, Xiaoming, Foote, Patrick H., Wu, Chung Wah, Devens, Mary E., Mahoney, Douglas W., Smyrk, Thomas C., Pannala, Rahul, Chari, Suresh T., Vege, Santhi Swaroop, Topazian, Mark D., Petersen, Bret T., Levy, Michael J., Rajan, Elizabeth, Gleeson, Ferga C., Dayyeh, Barham Abu, Nguyen, Cuong C., Faigel, Douglas O., Woodward, Timothy A., Wallace, Michael B., Petersen, Gloria, Allawi, Hatim T., Lidgard, Graham P., Kisiel, John B., Ahlquist, David A.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984349/
https://ncbi.nlm.nih.gov/pubmed/31323382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2019.07.017
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