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Identifying anti-prion chemical compounds using a newly established yeast high-throughput screening system

Prion-like protein aggregation underlies the pathology of a group of fatal neurodegenerative diseases in humans, including Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and transmissible spongiform encephalopathy (TSE). Currently, few high-throughput screen...

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Bibliografiska uppgifter
I publikationen:Cell Chem Biol
Huvudupphovsmän: Du, Zhiqiang, Valtierra, Stephanie, Cardona, Luzivette Robles, Dunne, Sara Fernandez, Luan, Chi-Hao, Li, Liming
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984038/
https://ncbi.nlm.nih.gov/pubmed/31668517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.10.004
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