Loss of PTEN-induced kinase 1 (Pink1) reduces hippocampal tyrosine hydroxylase and impairs learning and memory

Phosphatase and tensin homolog (PTEN)-induced kinase 1 (Pink1) is involved in mitochondrial quality control, which is essential for maintaining energy production and minimizing oxidative damage from dysfunctional/depolarized mitochondria. Pink1 mutations are the second most common cause of autosomal...

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發表在:Exp Neurol
Main Authors: Maynard, Mark E., Redell, John B., Kobori, Nobuhide, Underwood, Erica L., Fischer, Tara D., Hood, Kimberly N., LaRoche, Vincent, Waxham, M. Neal, Moore, Anthony N., Dash, Pramod K.
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984002/
https://ncbi.nlm.nih.gov/pubmed/31655049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.113081
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