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The Hsp90 Molecular Chaperone Regulates the Transcription Factor Network Controlling Chromatin Accessibility

Genomic events including gene regulation and chromatin status are controlled by transcription factors. Here we report that the Hsp90 molecular chaperone broadly regulates the transcription factor protein family. Our studies identified a biphasic use of Hsp90 in which early inactivation (15 min) of t...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Gvozdenov, Zlata, Bendix, Lindsey D., Kolhe, Janhavi, Freeman, Brian C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983977/
https://ncbi.nlm.nih.gov/pubmed/31628945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.09.007
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