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Deficient autophagy in epithelial stem cells drives aging in the freshwater cnidarian Hydra

Hydra possesses three distinct stem cell populations that continuously self-renew and prevent aging in Hydra vulgaris. However, sexual animals from the H. oligactis cold-sensitive strain Ho_CS develop an aging phenotype upon gametogenesis induction, initiated by the loss of interstitial stem cells....

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Tomczyk, Szymon, Suknovic, Nenad, Schenkelaars, Quentin, Wenger, Yvan, Ekundayo, Kazadi, Buzgariu, Wanda, Bauer, Christoph, Fischer, Kathleen, Austad, Steven, Galliot, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983715/
https://ncbi.nlm.nih.gov/pubmed/31862842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.177840
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