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The Anticancer Effects of Atractylenolide III Associate With the Downregulation of Jak3/Stat3-Dependent IDO Expression

Objective: Indoleamin-2,3-dioxygenase-1 (IDO) has been identified as a checkpoint protein involved in generating the immunosuppressive tumor microenvironment that supports tumor growth. It has been reported that atractylenolide III (ATLIII) has anticancer and immune modulatory effects. This study is...

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Vydáno v:Front Pharmacol
Hlavní autoři: Liu, Jun-bao, Chen, Dan, Bao, Ting-ting, Fan, Fang-tian, Yu, Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983677/
https://ncbi.nlm.nih.gov/pubmed/32038231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01505
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