Microglial IRF5-IRF4 regulatory axis regulates neuroinflammation after cerebral ischemia and impacts stroke outcomes

Microglial activation plays a central role in poststroke inflammation and causes secondary neuronal damage; however, it also contributes in debris clearance and chronic recovery. Microglial pro- and antiinflammatory responses (or so-called M1-M2 phenotypes) coexist and antagonize each other througho...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Al Mamun, Abdullah, Chauhan, Anjali, Qi, Shaohua, Ngwa, Conelius, Xu, Yan, Sharmeen, Romana, Hazen, Amy L., Li, Jun, Aronowski, Jaroslaw A., McCullough, Louise D., Liu, Fudong
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983422/
https://ncbi.nlm.nih.gov/pubmed/31892541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914742117
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