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Interactions of Paraoxonase-1 with Pharmacologically Relevant Carbamates

Mammalian paraoxonase-1 hydrolyses a very broad spectrum of esters such as certain drugs and xenobiotics. The aim of this study was to determine whether carbamates influence the activity of recombinant PON1 (rePON1). Carbamates were selected having a variety of applications: bambuterol and physostig...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Bosak, Anita, Bavec, Aljoša, Konte, Tilen, Šinko, Goran, Kovarik, Zrinka, Goličnik, Marko
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983073/
https://ncbi.nlm.nih.gov/pubmed/31947900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010211
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