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The Influence of Quadruplex Structure in Proximity to P53 Target Sequences on the Transactivation Potential of P53 Alpha Isoforms

p53 is one of the most studied tumor suppressor proteins that plays an important role in basic biological processes including cell cycle, DNA damage response, apoptosis, and senescence. The human TP53 gene contains alternative promoters that produce N-terminally truncated proteins and can produce se...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Porubiaková, Otília, Bohálová, Natália, Inga, Alberto, Vadovičová, Natália, Coufal, Jan, Fojta, Miroslav, Brázda, Václav
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982142/
https://ncbi.nlm.nih.gov/pubmed/31878115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010127
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