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Global Gene Expression Analysis Identifies Age-Related Differences in Knee Joint Transcriptome during the Development of Post-Traumatic Osteoarthritis in Mice

Aging and injury are two major risk factors for osteoarthritis (OA). Yet, very little is known about how aging and injury interact and contribute to OA pathogenesis. In the present study, we examined age- and injury-related molecular changes in mouse knee joints that could contribute to OA. Using RN...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sebastian, Aimy, Murugesh, Deepa K., Mendez, Melanie E., Hum, Nicholas R., Rios-Arce, Naiomy D., McCool, Jillian L., Christiansen, Blaine A., Loots, Gabriela G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982134/
https://ncbi.nlm.nih.gov/pubmed/31935848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010364
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