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A Novel Tissue and Stem Cell Specific TERF1 Splice Variant Is Downregulated in Tumour Cells

In this study, we describe the identification of a novel splice variant of TERF1/PIN2, one of the main components of the telomeric shelterin complex. This new splice variant is identical to TERF1, apart from a 30 amino acid internal insertion near to the C-terminus of TERF1. Based on genome comparis...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Morcos, Yousef Ashraf Tawfik, Najjar, Gregoire, Meessen, Sabine, Witt, Britta, Azoitei, Anca, Kumar, Mukesh, Wakileh, Gamal, Schwarz, Klaus, Schrezenmeier, Hubert, Zengerling, Friedemann, Bolenz, Christian, Günes, Cagatay
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981981/
https://ncbi.nlm.nih.gov/pubmed/31877678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010085
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