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Use of QSAR Global Models and Molecular Docking for Developing New Inhibitors of c-src Tyrosine Kinase

A prototype of a family of at least nine members, cellular Src tyrosine kinase is a therapeutically interesting target because its inhibition might be of interest not only in a number of malignancies, but also in a diverse array of conditions, from neurodegenerative pathologies to certain viral infe...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Ancuceanu, Robert, Tamba, Bogdan, Stoicescu, Cristina Silvia, Dinu, Mihaela
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981969/
https://ncbi.nlm.nih.gov/pubmed/31861445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010019
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