Cargando...

Screening and Identification of Novel cGAS Homologues Using a Combination of in Vitro and In Vivo Protein Synthesis

The cyclic GMP-AMP synthase (cGAS) catalyzes the synthesis of the multifunctional second messenger, cGAMP, in metazoans. Although numerous cGAS homologues are predicted in protein databases, the catalytic activity towards cGAMP synthesis has been proven for only four of them. Therefore, we selected...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Rolf, Jascha, Siedentop, Regine, Lütz, Stephan, Rosenthal, Katrin
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981698/
https://ncbi.nlm.nih.gov/pubmed/31877895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010105
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!