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Lixivaptan, a New Generation Diuretic, Counteracts Vasopressin-Induced Aquaporin-2 Trafficking and Function in Renal Collecting Duct Cells

Vasopressin V2 receptor (V2R) antagonists (vaptans) are a new generation of diuretics. Compared with classical diuretics, vaptans promote the excretion of retained body water in disorders in which plasma vasopressin concentrations are inappropriately high for any given plasma osmolality. Under these...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Di Mise, Annarita, Venneri, Maria, Ranieri, Marianna, Centrone, Mariangela, Pellegrini, Lorenzo, Tamma, Grazia, Valenti, Giovanna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981680/
https://ncbi.nlm.nih.gov/pubmed/31888044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010183
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