Ipragliflozin Ameliorates Endoplasmic Reticulum Stress and Apoptosis through Preventing Ectopic Lipid Deposition in Renal Tubules

Background: Chronic kidney disease (CKD) and non-alcoholic steatohepatitis (NASH) are major health burdens closely related to metabolic syndrome. A link between CKD and NASH has been assumed; however, the underlying mechanism is still unknown. Ectopic lipid deposition (ELD) in the hepatocyte results...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hosokawa, Kohshiro, Takata, Tomoaki, Sugihara, Takaaki, Matono, Tomomitsu, Koda, Masahiko, Kanda, Tsutomu, Taniguchi, Sosuke, Ida, Ayami, Mae, Yukari, Yamamoto, Marie, Iyama, Takuji, Fukuda, Satoko, Isomoto, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981520/
https://ncbi.nlm.nih.gov/pubmed/31888083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010190
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