Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain

Extracellular vesicles (EVs) derived from human bone marrow mesenchymal stem cells (hMSCs) have great promise as biologics to treat neurological and neurodegenerative conditions due to their robust antiinflammatory and neuroprotective properties. Besides, intranasal (IN) administration of EVs has ca...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Kodali, Maheedhar, Castro, Olagide W., Kim, Dong-Ki, Thomas, Alicia, Shuai, Bing, Attaluri, Sahithi, Upadhya, Raghavendra, Gitai, Daniel, Madhu, Leelavathi N., Prockop, Darwin J., Shetty, Ashok K.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981466/
https://ncbi.nlm.nih.gov/pubmed/31888012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010181
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