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Harnessing the Effects of BTKi on T Cells for Effective Immunotherapy against CLL
B-cell receptor (BCR) signaling and tumor–microenvironment crosstalk both drive chronic lymphocytic leukemia (CLL) pathogenesis. Within the microenvironment, tumor cells shape the T-cell compartment, which in turn supports tumor growth and survival. Targeting BCR signaling using Bruton tyrosine kina...
Enregistré dans:
| Publié dans: | Int J Mol Sci |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6981459/ https://ncbi.nlm.nih.gov/pubmed/31861854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010068 |
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