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Mechanisms controlling PD-L1 expression in cancer

The engagement of programmed cell death protein 1 (PD-1; encoded by the PDCD1 gene) receptor expressed on activated T cells and its ligand programmed death-ligand 1 (PD-L1; encoded by the CD274 gene) is a major co-inhibitory checkpoint signaling that controls T-cell activities. Various types of canc...

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Publicat a:Mol Cell
Autors principals: Cha, Jong-Ho, Chan, Li-Chuan, Li, Chia-Wei, Hsu, Jennifer L., Hung, Mien-Chie
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981282/
https://ncbi.nlm.nih.gov/pubmed/31668929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.09.030
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