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Defective transcription of ATF3 responsive genes, a marker for Cockayne Syndrome
Cockayne syndrome (CS) is a rare genetic disorder caused by mutations (dysfunction) in CSA and CSB. CS patients exhibit mild photosensitivity and severe neurological problems. Currently, CS diagnosis is based on the inefficiency of CS cells to recover RNA synthesis upon genotoxic (UV) stress. Indeed...
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| Gepubliceerd in: | Sci Rep |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6981198/ https://ncbi.nlm.nih.gov/pubmed/31980658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57999-4 |
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