Redefining Phenotypes to Advance Psychiatric Genetics: Implications from Hierarchical Taxonomy of Psychopathology

Genetic discovery in psychiatry and clinical psychology is hindered by suboptimal phenotypic definitions. We argue that the hierarchical, dimensional, and data-driven classification system proposed by the Hierarchical Taxonomy of Psychopathology (HiTOP) consortium provides a more effective approach...

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Detalhes bibliográficos
Publicado no:J Abnorm Psychol
Main Authors: Waszczuk, Monika A., Eaton, Nicholas R., Krueger, Robert F., Shackman, Alexander J., Waldman, Irwin D., Zald, David H., Lahey, Benjamin B., Patrick, Christopher J., Conway, Christopher C., Ormel, Johan, Hyman, Steven E., Fried, Eiko I., Forbes, Miriam K., Docherty, Anna R., Althoff, Robert R., Bach, Bo, Chmielewski, Michael, DeYoung, Colin G., Forbush, Kelsie T., Hallquist, Michael, Hopwood, Christopher J., Ivanova, Masha Y., Jonas, Katherine G., Latzman, Robert D., Markon, Kristian E., Mullins-Sweatt, Stephanie N., Pincus, Aaron L., Reininghaus, Ulrich, South, Susan C., Tackett, Jennifer L., Watson, David, Wright, Aidan G. C., Kotov, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980897/
https://ncbi.nlm.nih.gov/pubmed/31804095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/abn0000486
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