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Improved trafficking and expression of luminopsins for more efficient optical and pharmacological control of neuronal activity

Luminopsins (LMOs) are chimeric proteins consisting of a luciferase fused to an opsin that provide control of neuronal activity, allowing for less cumbersome and less invasive optogenetic manipulation. It was previously shown that both an external light source and the luciferase substrate, coelenter...

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Dettagli Bibliografici
Pubblicato in:J Neurosci Res
Autori principali: Zhang, James Y., Tung, Jack K., Wang, Zuhui, Yu, Shan Ping, Gross, Robert E., Wei, Ling, Berglund, Ken
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980770/
https://ncbi.nlm.nih.gov/pubmed/31670406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.24546
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