Clinical utility of plasma cell-free DNA in adult patients with newly diagnosed glioblastoma – a pilot prospective study

PURPOSE: The clinical utility of plasma cell-free DNA (cfDNA) has not been assessed prospectively in patients with glioblastoma (GBM). We aimed to determine the prognostic impact of plasma cfDNA in GBM, as well as its role as a surrogate of tumor burden and substrate for next-generation sequencing (...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Bagley, Stephen J., Nabavizadeh, S. Ali, Mays, Jazmine J., Till, Jacob E., Ware, Jeffrey B., Levy, Scott, Sarchiapone, Whitney, Hussain, Jasmin, Prior, Timothy, Guiry, Samantha, Christensen, Theresa, Yee, Stephanie S., Nasrallah, MacLean P., Morrissette, Jennifer J.D., Binder, Zev A., O’Rourke, Donald M., Cucchiara, Andrew J., Brem, Steven, Desai, Arati S., Carpenter, Erica L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980766/
https://ncbi.nlm.nih.gov/pubmed/31666247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-2533
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