Dysfunction of Oskyddad causes Harlequin-type ichthyosis-like defects in Drosophila melanogaster

Prevention of desiccation is a constant challenge for terrestrial organisms. Land insects have an extracellular coat, the cuticle, that plays a major role in protection against exaggerated water loss. Here, we report that the ABC transporter Oskyddad (Osy)—a human ABCA12 paralog—contributes to the w...

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Udgivet i:PLoS Genet
Main Authors: Wang, Yiwen, Norum, Michaela, Oehl, Kathrin, Yang, Yang, Zuber, Renata, Yang, Jing, Farine, Jean-Pierre, Gehring, Nicole, Flötenmeyer, Matthias, Ferveur, Jean-François, Moussian, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980720/
https://ncbi.nlm.nih.gov/pubmed/31929524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008363
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