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Prior stress followed by a novel stress challenge results in sex-specific deficits in behavioral flexibility and changes in gene expression in rat medial prefrontal cortex.

Chronic stress leads to sex-specific changes in the structure and function of rat medial prefrontal cortex (mPFC). Little is known about whether these effects persist following the cessation of chronic stress, or how these initial effects may impact responses to future stressors. Here we examined at...

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Detalhes bibliográficos
Publicado no:Horm Behav
Main Authors: Moench, Kelly M., Breach, Michaela R., Wellman, Cara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980662/
https://ncbi.nlm.nih.gov/pubmed/31634476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2019.104615
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