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An In Vitro and In Vivo Comparison of Cartilage Growth in Chondrocyte-Laden Matrix Metalloproteinase-Sensitive Poly(Ethylene Glycol) Hydrogels with Localized Transforming Growth Factor β3

While matrix-assisted autologous chondrocyte implantation has emerged as a promising therapy to treat focal chondral defects, matrices that support regeneration of hyaline cartilage remain challenging. The goal of this work was to investigate the potential of a matrix metalloproteinase (MMP)-sensiti...

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Détails bibliographiques
Publié dans:Acta Biomater
Auteurs principaux: Schneider, Margaret C., Chu, Stanley, Randolph, Mark A., Bryant, Stephanie J.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980342/
https://ncbi.nlm.nih.gov/pubmed/30914256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2019.03.046
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