Ubiquitin-Specific Protease 8 Mutant Corticotrope Adenomas Present Unique Secretory and Molecular Features and Shed Light on the Role of Ubiquitylation on ACTH Processing

BACKGROUND: Somatic mutations in the ubiquitin-specific protease 8 (USP8) gene have recently been shown to occur in ACTH-secreting pituitary adenomas, thus calling attention to the ubiquitin system in corticotrope adenomas. OBJECTIVES: Assess the consequences of USP8 mutations and establish the role...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Neuroendocrinology
Main Authors: Sesta, Antonella, Cassarino, Maria Francesca, Terreni, Mariarosa, Ambrogio, Alberto G., Libera, Laura, Bardelli, Donatella, Lasio, Giovanni, Losa, Marco, Pecori Giraldi, Francesca
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979434/
https://ncbi.nlm.nih.gov/pubmed/31280266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000500688
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker