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Investigation of toll-like receptor (TLR) 4 inhibitor TAK-242 as a new potential anti-rheumatoid arthritis drug

BACKGROUND: Proper blocking of toll-like receptor (TLR) activation during disease progression has been reported to have inhibitory effect on the pathogenesis of rheumatoid arthritis (RA). We tested whether the TLR4 inhibitor TAK-242 had potential as a remedy for rheumatoid arthritis. METHODS: The th...

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Bibliografische gegevens
Gepubliceerd in:Arthritis Res Ther
Hoofdauteurs: Samarpita, Snigdha, Kim, Joo Young, Rasool, Mahaboob Khan, Kim, Kyoung Soo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979396/
https://ncbi.nlm.nih.gov/pubmed/31973752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-2097-2
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