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Co-opted transposons help perpetuate conserved higher-order chromosomal structures

BACKGROUND: Transposable elements (TEs) make up half of mammalian genomes and shape genome regulation by harboring binding sites for regulatory factors. These include binding sites for architectural proteins, such as CTCF, RAD21, and SMC3, that are involved in tethering chromatin loops and marking d...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Choudhary, Mayank NK, Friedman, Ryan Z., Wang, Julia T., Jang, Hyo Sik, Zhuo, Xiaoyu, Wang, Ting
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979391/
https://ncbi.nlm.nih.gov/pubmed/31973766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1916-8
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