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Computational design of syntheses leading to compound libraries or isotopically labelled targets

Although computer programs for retrosynthetic planning have shown improved and in some cases quite satisfactory performance in designing routes leading to specific, individual targets, no algorithms capable of planning syntheses of entire target libraries – important in modern drug discovery – have...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Molga, Karol, Dittwald, Piotr, Grzybowski, Bartosz A.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979321/
https://ncbi.nlm.nih.gov/pubmed/32055308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02678a
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