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MLH1 promoter hypermethylation in uterine carcinosarcoma rarely coexists with TP53 mutation

INTRODUCTION: Carcinosarcoma (CS) is an infrequent neoplasm composed of a carcinomatous and a sarcomatous element. Its molecular pathogenesis is poorly understood. In this study, we investigated the disturbances in the immunohistochemical expression of p53 and mismatch repair (MMR) proteins, as well...

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Detalhes bibliográficos
Publicado no:Contemp Oncol (Pozn)
Main Authors: Kunc, Michal, Gabrych, Anna, Rekawiecki, Bartlomiej, Gorczynski, Adam, Franke, Sabine, Haybaeck, Johannes, Biernat, Wojciech, Czapiewski, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: Termedia Publishing House 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978758/
https://ncbi.nlm.nih.gov/pubmed/31992951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/wo.2019.89635
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