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Toxicity evaluation and nasal mucosal tissue deposition of dexamethasone-infused mucoadhesive in situ nasal gelling systems

To demonstrate safety of a developed intranasal dexamethasone-infused in situ gelling formulation, quantification of a validated clinical biomarker indicative of cytotoxic potential using a human sinonasal explant model was first confirmed. Systematic cytotoxicity studies using the lactate dehydroge...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Principais autores: Pandey, Preeti, Pandey, Saurabh, Cabot, Peter J., Wallwork, Benjamin, Panizza, Benedict J., Parekh, Harendra S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978612/
https://ncbi.nlm.nih.gov/pubmed/31997897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2019.06.005
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