NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons

Activation of Agouti-Related Peptide (AgRP)-expressing neurons promotes feeding and insulin resistance. Here, we examine the contribution of neuropeptide Y (NPY)-dependent signaling to the diverse physiological consequences of activating AgRP neurons. NPY-deficient mice fail to rapidly increase food...

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Udgivet i:Nat Commun
Main Authors: Engström Ruud, Linda, Pereira, Mafalda M. A., de Solis, Alain J., Fenselau, Henning, Brüning, Jens C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978463/
https://ncbi.nlm.nih.gov/pubmed/31974377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14291-3
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