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Easy access to medium-sized lactones through metal carbene migratory insertion enabled 1,4-palladium shift

Reactions that efficiently construct medium-sized lactones are significant, as they overcome the unfavorable entropic factor and transannular interactions for ring closure, and the lactones produced are common structural motifs recurring in many biologically active compounds. Herein, we describe a v...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Yu, Yinghua, Chakraborty, Pushkin, Song, Jinshuai, Zhu, Lei, Li, Chunsen, Huang, Xueliang
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978448/
https://ncbi.nlm.nih.gov/pubmed/31974346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14101-5
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