Hypomethylation of MIR‐378 5’‐flanking region predicts poor survival in young patients with myelodysplastic syndrome

BACKGROUND: Previous studies have disclosed up‐regulation of MIR‐378 in acute myeloid leukemia (AML), and might consequently affect the outcome of the patients. Correspondingly, hypomethylation of MIR‐378 was also identified in AML, particularly for FAB‐M2 subtype with t(8;21) chromosomal translocat...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Wu, De‐hong, Zhu, Xiao‐wen, Wen, Xiang‐mei, Zhang, Ying‐ying, Ma, Ji‐chun, Yao, Dong‐ming, Zhou, Jing‐dong, Guo, Hong, Wu, Peng‐fei, Zhang, Xing‐li, Qiu, Hong‐chun, Lin, Jiang, Qian, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978398/
https://ncbi.nlm.nih.gov/pubmed/31833222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1067
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