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Antibody-based delivery of TNF to the tumor neo-vasculature potentiates the therapeutic activity of a peptide anti-cancer vaccine

There is a growing interest in the use of tumor antigens for therapeutic vaccination strategies. Unfortunately, in most cases, the use of peptide vaccines in patients does not mediate shrinkage of solid tumor masses. Here, we studied the opportunity to boost peptide vaccination with F8-TNF, an antib...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Probst, Philipp, Stringhini, Marco, Ritz, Danilo, Fugmann, Tim, Neri, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978140/
https://ncbi.nlm.nih.gov/pubmed/30327303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1728
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