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Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas
Key to CRISPR-Cas adaptive immunity is maintaining an ongoing record of invading nucleic acids, a process carried out by the Cas1-Cas2 complex that integrates short segments of foreign genetic material (spacers) into the CRISPR locus. It is hypothesized that Cas1 evolved from casposases, a novel cla...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6977970/ https://ncbi.nlm.nih.gov/pubmed/31913120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50004 |
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