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L-type Calcium Channels are Involved in Iron-induced Neurotoxicity in Primary Cultured Ventral Mesencephalon Neurons of Rats

In the present study, we investigated the mechanisms underlying the mediation of iron transport by L-type Ca(2+) channels (LTCCs) in primary cultured ventral mesencephalon (VM) neurons from rats. We found that co-treatment with 100 µmol/L FeSO(4) and MPP(+) (1-methyl-4-phenylpyridinium) significantl...

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Bibliographische Detailangaben
Veröffentlicht in:Neurosci Bull
Hauptverfasser: Xu, Yu-Yu, Wan, Wen-Ping, Zhao, Sha, Ma, Ze-Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Singapore 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977792/
https://ncbi.nlm.nih.gov/pubmed/31482520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-019-00424-2
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