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Aromatase deficiency in hematopoietic cells improves glucose tolerance in male mice through skeletal muscle-specific effects

Estrogens are important for maintaining metabolic health in males. However, the key sources of local estrogen production for regulating energy metabolism have not been fully defined. Immune cells exhibit aromatase activity and are resident in metabolic tissues. To determine the relative contribution...

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Udgivet i:PLoS One
Main Authors: Rubinow, Katya B., den Hartigh, Laura J., Goodspeed, Leela, Wang, Shari, Oz, Orhan K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977739/
https://ncbi.nlm.nih.gov/pubmed/31971970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227830
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