Evaluation of anti-inflammatory activity and molecular docking study of new aza-bicyclic isoxazoline acylhydrazone derivatives

The aim of this study was to investigate the anti-inflammatory effects of two new isoxazoline-acylhydrazone derivatives: N′-(4-methoxybenzylidene)-6-(4-nitro-benzoyl)-3a,5,6,6a-tetrahydro-4H-pyrrolo[3,2-d]isoxazole-3-carbohydrazide (R-123) and N′-(4-chlorobenzylidene)-6-(4-chlorobenzoyl)-3a,5,6,6a-t...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Mota, Fernanda Virginia Barreto, de Araújo Neta, Marlene Saraiva, de Souza Franco, Eryvelton, Bastos, Isla Vanessa Gomes Alves, da Araújo, Larissa Cardoso Correia, da Silva, Sandra Cabral, de Oliveira, Tatiane Bezerra, Souza, Eduarda Karynne, de Almeida, Valderes Moraes, Ximenes, Rafael Matos, de Sousa Maia, Maria Bernadete, Junior, Francisco Jaime Bezerra Mendonça, Marchand, Pascal, de Faria, Antônio Rodolfo, da Silva, Teresinha Gonçalves
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977463/
https://ncbi.nlm.nih.gov/pubmed/32133104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00276f
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