Contribution of genetic polymorphism of methylene tetrahydrofolate reductase on the effect of methotrexate in ectopic pregnancy patients

BACKGROUND: Methotrexate (MTX) is the prior drug in ectopic pregnancy (EP). However, approximately 10% of patients suffer from failure by MTX therapy. Reduced folate carrier 1 (RFC1), methylene tetrahydrofolate reductase (MTHFR), and dihydrofolate reductase (DHFR) are involved in the transport and e...

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Bibliografiske detaljer
Udgivet i:J Clin Lab Anal
Main Authors: Deng, Jie, Chen, Li, Xue, Heng, Zeng, Fan‐Xiang, Niu, Pei‐Guang, Shi, Dao‐Hua
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977338/
https://ncbi.nlm.nih.gov/pubmed/31502727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23030
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