Immunological effects of adjuvants in subsets of antigen presenting cells of cancer patients undergoing chemotherapy

BACKGROUND: We have previously shown that HCC patients and healthy subjects are equally responsive to a RNAdjuvant(®), a novel TLR-7/8/RIG-I agonist based on noncoding RNA developed by CureVac, by an ex vivo evaluation. However, the immunological effect of adjuvants on immune cells from cancer patie...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Mauriello, Angela, Manolio, Carmen, Cavalluzzo, Beatrice, Avallone, Antonio, Borrelli, Marco, Morabito, Alessandro, Iovine, Emanuele, Chambery, Angela, Russo, Rosita, Tornesello, Maria Lina, Buonaguro, Franco M., Tagliamonte, Maria, Buonaguro, Luigi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977281/
https://ncbi.nlm.nih.gov/pubmed/31973714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02218-x
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