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Tailor-made solvents for pharmaceutical use? Experimental and computational approach for determining solubility in deep eutectic solvents (DES)

A deep eutectic solvent (DES) is a mixture of two or more chemicals that interact via hydrogen bonding and has a melting point far below that of the individual components. DESs have been proposed as alternative solvents for poorly soluble active pharmaceutical ingredients (API). In this study, the s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Pharm X
Hauptverfasser: Palmelund, Henrik, Andersson, Martin P., Asgreen, Camilla J., Boyd, Ben J., Rantanen, Jukka, Löbmann, Korbinian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977171/
https://ncbi.nlm.nih.gov/pubmed/31993583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2019.100034
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