Staphylococcus aureus Isolated from Skin from Atopic-Dermatitis Patients Produces Staphylococcal Enterotoxin Y, Which Predominantly Induces T-Cell Receptor Vα-Specific Expansion of T Cells

While investigating the virulence traits of Staphylococcus aureus adhering to the skin of atopic-dermatitis (AD) patients, we identified a novel open reading frame (ORF) with structural similarity to a superantigen from genome sequence data of an isolate from AD skin. Concurrently, the same ORF was...

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Gepubliceerd in:Infect Immun
Hoofdauteurs: Aziz, Fatkhanuddin, Hisatsune, Junzo, Yu, Liansheng, Kajimura, Junko, Sato’o, Yusuke, Ono, Hisaya K., Masuda, Kanako, Yamaoka, Mika, Salasia, Siti Isrina Oktavia, Nakane, Akio, Ohge, Hiroki, Kusunoki, Yoichiro, Sugai, Motoyuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2020
Onderwerpen:
Molecular Pathogenesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977126/
https://ncbi.nlm.nih.gov/pubmed/31740530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00360-19
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