Development and Validation of a New Gas Chromatography–Tandem Mass Spectrometry Method for the Measurement of Enrichment of Glyoxylate Metabolism Analytes in Hyperoxaluria Patients Using a Stable Isotope Procedure

[Image: see text] Primary hyperoxalurias (PH) are inborn errors of glyoxylate metabolism characterized by an increase in endogenous oxalate production. Oxalate overproduction may cause calcium-oxalate crystal formation leading to kidney stones, nephrocalcinosis, and ultimately kidney failure. Twenty...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Anal Chem
Prif Awduron: van Harskamp, Dewi, Garrelfs, Sander F., Oosterveld, Michiel J. S., Groothoff, Jaap W., van Goudoever, Johannes B., Schierbeek, Henk
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2019
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977104/
https://ncbi.nlm.nih.gov/pubmed/31867958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b03670
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