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Bioengineered miR-328-3p modulates GLUT1-mediated glucose uptake and metabolism to exert synergistic antiproliferative effects with chemotherapeutics

MicroRNAs (miRNAs or miRs) are small noncoding RNAs derived from genome to control target gene expression. Recently we have developed a novel platform permitting high-yield production of bioengineered miRNA agents (BERA). This study is to produce and utilize novel fully-humanized BERA/miR-328-3p mol...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Yi, Wanrong, Tu, Mei-Juan, Liu, Zhenzhen, Zhang, Chao, Batra, Neelu, Yu, Ai-Xi, Yu, Ai-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976971/
https://ncbi.nlm.nih.gov/pubmed/31993313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.11.001
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