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Microtubule-targeting anticancer drug eribulin induces drug efflux transporter P-glycoprotein
This study examined the effects of microtubule-targeting anticancer drugs (paclitaxel, cabazitaxel, and eribulin) on the expression of drug efflux transporter P-glycoprotein, which is encoded by MDR1. Paclitaxel and eribulin induced MDR1 promoter activity in a concentration-dependent manner, while c...
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| Publicado en: | Biochem Biophys Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6976863/ https://ncbi.nlm.nih.gov/pubmed/31993509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100727 |
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