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The Upregulation of OCT4 in Acidic Extracellular pH is Associated with Gemcitabine Resistance in Cholangiocarcinoma Cell Lines

BACKGROUND: Cholangiocarcinoma (CCA), although is an uncommon liver cancer originating from bile duct epithelial cells, is one of the top 10 most fatal cancers. Chemoresistance is an unmet need always found in CCA patients. Tumor microenvironment conditions such as hypoxia, nutrient starvation and a...

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Publicat a:Asian Pac J Cancer Prev
Autors principals: Choodetwattana, Phatchareeporn, Proungvitaya, Siriporn, Jearanaikoon, Patcharee, Limpaiboon, Temduang
Format: Artigo
Idioma:Inglês
Publicat: West Asia Organization for Cancer Prevention 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976837/
https://ncbi.nlm.nih.gov/pubmed/31554372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31557/APJCP.2019.20.9.2745
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