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Ursodeoxycholic Acid Attenuates the Retinal Vascular Abnormalities in Anti-PDGFR-β Antibody-Induced Pericyte Depletion Mouse Models

As a clinical manifestations of diabetic retinopathy (DR), pericytes (PCs) loss from the capillary walls is thought to be an initial pathological change responsible for the breakdown of the blood-retinal barrier (BRB). This study was performed to investigate the effects of ursodeoxycholic acid (UDCA...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shiraya, Tomoyasu, Araki, Fumiyuki, Ueta, Takashi, Fukunaga, Hisako, Totsuka, Kiyohito, Arai, Takahiro, Uemura, Akiyoshi, Moriya, Kyoji, Kato, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976624/
https://ncbi.nlm.nih.gov/pubmed/31969665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58039-x
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