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Comparative expression analysis in small cell lung carcinoma reveals neuroendocrine pattern change in primary tumor versus lymph node metastases

BACKGROUND: Recent preclinical data suggest that neuroendocrine (NE) subtype of small cell lung cancer (SCLC) has strong therapeutic relevance. NE high tumors are associated with immune desert and NE low tumors are considered to have an immune oasis phenotype. Our aim was to investigate the NE pheno...

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Detalhes bibliográficos
Publicado no:Transl Lung Cancer Res
Main Authors: Lohinai, Zoltan, Megyesfalvi, Zsolt, Suda, Kenichi, Harko, Tunde, Ren, Shengxiang, Moldvay, Judit, Laszlo, Viktoria, Rivard, Christopher, Dome, Balazs, Hirsch, Fred R.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976364/
https://ncbi.nlm.nih.gov/pubmed/32010572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2019.11.30
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