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Compression-induced dedifferentiation of adipocytes promotes tumor progression

Dysregulated physical stresses are generated during tumorigenesis that affect the surrounding compliant tissues including adipocytes. However, the effect of physical stressors on the behavior of adipocytes and their cross-talk with tumor cells remain elusive. Here, we demonstrate that compression of...

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Pubblicato in:Sci Adv
Autori principali: Li, Yiwei, Mao, Angelo S., Seo, Bo Ri, Zhao, Xing, Gupta, Satish Kumar, Chen, Maorong, Han, Yu Long, Shih, Ting-Yu, Mooney, David J., Guo, Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976290/
https://ncbi.nlm.nih.gov/pubmed/32010780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax5611
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